ストレプトグリシンB

ストレプトグリシンB(Streptogrisin B、EC 3.4.21.81)は、以下の化学反応を触媒する酵素である^[1]^[2]^[3]^[4]^[5]。

トリプシンと類似した特異性で、タンパク質を加水分解する。

この酵素は、Streptomyces griseusから単離された。

出典

^ Jurasek, L., Fackre, D. and Smillie, L.B. (1969). “Remarkable homology about the disulfide bridges of a trypsin-like enzyme from Streptomyces griseus”. Biochem. Biophys. Res. Commun. 37: 99-105. PMID 4899581.
^ Fujinaga, M., Read, R.J., Sielecki, A., Ardelt, W., Laskowski, M., Jr. and James, M.N.G. (1982). “Refined crystal structure of the molecular complex of Streptomyces griseus protease B, a serine protease, with the third domain of the ovomucoid inhibitor from turkey”. Proc. Natl Acad. Sci. USA 79: 4868-4872. PMID 6750612.
^ Read, R.J., Fujinaga, M., Sielecki, A.R. and James, M.N.G. (1983). “Structure of the complex of Streptomyces griseus protease B and the third domain of turkey ovomucoid inhibitor at 1.8-Å resolution”. Biochemistry 22: 4420-4433. PMID 6414511.
^ Henderson, G., Krygsman, P., Liu, C.J., Davey, C.C. and Malek, L.T. (1987). “Characterization and structure of genes for proteases A and B from Streptomyces griseus”. J. Bacteriol. 169: 3778-3784. PMID 3112129.
^ Greenblatt, H.M., Ryan, C.A. and James, M.N.G. (1989). “Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2.1 Å resolution”. J. Mol. Biol. 205: 201-228. PMID 2494344.