ストレプトグリシンA

ストレプトグリシンA(Streptogrisin A、EC 3.4.21.80)は、以下の化学反応を触媒する酵素である^[1]^[2]^[3]^[4]^[5]。

キモトリプシンと類似した特異性で、タンパク質を加水分解する。

この酵素は、Streptomyces griseusから単離された。

出典

^ Johnson, P. and Smillie, L.B. (1971). “The disulfide bridge sequences of a serine protease of wide specificity from Streptomyces griseus”. Can. J. Biochem. 49: 548-562. PMID 5575653.
^ Sielecki, A.R., Hendrickson, W.A., Broughton, C.G., Delbaere, L.T.J., Brayer, G.D. and James, M.N.G. (1979). “Protein structure refinement: Streptomyces griseus serine protease A at 1.8 Å resolution”. J. Mol. Biol. 134: 781-804. PMID 119870.
^ James, M.N.G., Sielecki, A.R., Brayer, G.D., Delbaere, L.T.J. and Bauer, C.-A. (1980). “Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 Å resolution”. J. Mol. Biol. 144: 43-88. PMID 6783761.
^ Delbaere, L.T.J. and Brayer, G.D. (1985). “The 1.8 Å structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates”. J. Mol. Biol. 183: 89-103. PMID 3892018.
^ Henderson, G., Krygsman, P., Liu, C.J., Davey, C.C. and Malek, L.T. (1987). “Characterization and structure of genes for proteases A and B from Streptomyces griseus”. J. Bacteriol. 169: 3778-3784. PMID 3112129.